Translational Paradigms in Cerebrovascular Gene Transfer

Translational informatics: enabling high-throughput research paradigms.

A common thread throughout the clinical and translational research domains is the need to collect, manage, integrate, analyze, and disseminate large-scale, heterogeneous biomedical data sets. However, well-established and broadly adopted theoretical and practical frameworks and models intended to address such needs are conspicuously absent in the published literature or other reputable knowledg...

Translational research in oncology: key bottlenecks and new paradigms.

Translational research is about transforming progress in basic research into products that benefit patients. Here I discuss some of the key obstacles to effective translational research in oncology that have previously received limited attention. Basic research often does not go far enough for straightforward clinical translation, and long-term, high-risk endeavours to fill these key gaps have ...

Gene repression paradigms in animal cells.

Review in translational hematology Side effects of retroviral gene transfer into hematopoietic stem cells

http://bloodjournal.hematologylibrary.org/content/101/6/2099.full.html Updated information and services can be found at: (58 articles) Reviews in Translational Hematology • Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entire...

A Transfer Learning Approach for Adaptive Classification in P300 Paradigms

Introduction: The P300 is one of the most widely used brain responses in BCIs today, popularized by none other than the P300 speller itself. However, most systems still require significant subject-specific training to achieve accurate, reliable classification of brain signals. We present an approach to classification that allows for classification with zero subject-specific data and also improv...